Method for direct chemical binding of d-dimer from a...

G - Physics – 01 – N

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G01N 33/53 (2006.01) G01N 33/86 (2006.01)

Patent

CA 2023354

A method and test kit to perform a simple detection assay for D-dimer, a fibrin breakdown product, which utilizes purified Fragment E of human fibrinogen attached to a solid phase for direct chemical binding of D-dimer from a biological sample. This direct binding method to assay for D-dimer of the present invention can be performed in a number of ways. In one embodiment of the invention, Fragment E is conjugated to latex carrier particles and an agglutination assay performed.

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