Method for directed cell in-growth and controlled tissue...

Details Method for directed cell in-growth and controlled tissue... Method for directed cell in-growth and controlled tissue...

A - Human Necessities

61

L

A61L 31/04 (2006.01)

Patent

CA 2651941

The present invention relates to a method for directed cell in-growth and controlled tissue regeneration to prevent post-surgical or post-traumatic adhesion and fibrosis formation on the injured surface of a tissue selected from the group consisting of spinal column tissue, dura mater, and spinal nerves in a mammal, comprising the step of providing, covering and separating the tissue with a bioactive biofunctional, non-porous, microscopically multilayered collagen foil biomatrix, and to a method for treating a defect in a mammal comprising the step of providing, covering and separating said tissue with a bioactive biofunctional, non-porous, microscopically multilayered collagen foil biomatrix.

L'invention concerne un procédé pour réguler l'invasion cellulaire et la régénération tissulaire, afin d'empêcher une adhérence post-chirurgicale et post-traumatique et la formation d'une fibrose à la surface d'un tissu présentant une lésion, ce tissu étant sélectionné dans le groupe comprenant les tissus de la colonne vertébrale, la dure-mère, et les nerfs rachidiens, chez un mammifère. Le procédé selon l'invention comprend les étapes qui consistent à fournir un tissu, à le couvrir, et à le séparer au moyen d'une biomatrice constituée d'une feuille de collagène non poreuse, bioactive et biofonctionnelle, qui comporte plusieurs couches microscopiques. Cette invention concerne également un procédé pour traiter un défaut chez un mammifère, ce procédé consistant à fournir un tissu, à le couvrir, et à le séparer au moyen d'une biomatrice constituée d'une feuille de collagène non poreuse, bioactive et biofonctionnelle, qui comporte plusieurs couches microscopiques.

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