Method for early imaging of atherosclerosis

Details Method for early imaging of atherosclerosis Method for early imaging of atherosclerosis

A - Human Necessities

61

K

A61K 49/00 (2006.01) A61K 51/04 (2006.01) A61B 5/055 (2006.01) A61B 6/12 (2006.01)

Patent

CA 2754492

The invention relates to methods of detecting active atherosclerotic plaques associated with blood vessel walls wherein the plaques comprise activated macrophages having accessible binding sites for a ligand. In one embodiment, plaques that block from about 2% to about 60% of the lumen of a blood vessel can be detected.

La présente invention concerne des méthodes de détection de plaques athérosclérotiques actives associées à des parois de vaisseau sanguin. Lesdites plaques comprennent des macrophages activés avec des sites de liaison accessibles pour un ligand. Dans un mode de réalisation, des plaques bloquant environ 2 % à environ 60 % de la lumière d'un vaisseau sanguin peuvent être détectées.

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