G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 27/416 (2006.01) C12Q 1/68 (2006.01) G01N 27/327 (2006.01)
Patent
CA 2441180
A convenient and commonly applicable method for the specific detection of a nucleic acid with an arbitrary sequence is provide. This method comprises attaching at least a nucleic acid single strand to an electrode, bringing the thus-obtained modified electrode in contact with a solution containing the analyte single-stranded nucleic acid, and measuring the redox reaction of the redox marker.
L'invention concerne un procédé pratique et communément applicable, consistant à détecter spécifiquement un acide nucléique comprenant une séquence arbitraire. Ce procédé consiste à relier au moins un brin unique d'acides nucléiques à une électrode; à mettre en contact l'électrode modifiée ainsi obtenue avec une solution contenant le brin unique d'acides nucléiques devant être analysé et un marqueur d'oxydoréduction; puis à mesurer la réaction d'oxydoréduction dudit marqueur.
Aoki Hiroshi
Umezawa Yoshio
Japan Science And Technology Corporation
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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