Method for elevating prolactin in mammals

Details Method for elevating prolactin in mammals Method for elevating prolactin in mammals

A - Human Necessities

61

K

A61K 38/07 (2006.01) A61K 31/00 (2006.01) A61K 38/11 (2006.01) A61P 5/06 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2653072

Methods for elevating and stabilizing prolactin levels in a mammal including methods of treating disorders and conditions associated with reduced serum levels of prolactin are provided. Also provided are methods of using certain synthetic tetrapeptide amides which are peripherally selective kappa opioid receptor agonists to elevate or stabilize serum prolactin levels.

L'invention concerne des procédés destinés à élever et à stabiliser des niveaux de prolactine chez des mammifères. Ces procédés comprennent des procédés permettant de traiter des troubles et des états pathologiques associés à des niveaux de prolactine réduits dans le sérum. L'invention concerne des procédés d'utilisation de certains amides tétrapeptidiques synthétiques qui sont des agonistes de récepteurs de kappa-opioïdes périphériquement sélectifs, lesquels procédés étant destinés à élever ou à stabiliser des niveaux de prolactine dans le sérum.

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