Method for enhancing the bioavailability of ospemifene

Details Method for enhancing the bioavailability of ospemifene Method for enhancing the bioavailability of ospemifene

A - Human Necessities

61

K

A61K 31/085 (2006.01)

Patent

CA 2556089

This invention relates to a method for enhancing the bioavailability of ospemifene or a geometric isomer, a stereoisomer, a pharmaceutically active salt, an ester thereof or a metabolite thereof, wherein said compound is administered orally to the individual in connection with the intake of food. The invention also relates to the treatment or prevention of osteoporosis, skin atrophy, epithelial and mucosal atrophy, as well as to treatment or prevention of urinary or vaginal symptoms.

Cette invention concerne un procédé d'amélioration de la biodisponibilité d'ospémifène ou d'un isomère géométrique, un stéréoisomère, un sel pharmaceutiquement acceptable, un ester de celui-ci ou un métabolite de celui-ci, ledit composé est administré par voie orale à un individu en association avec la prise d'aliment. L'invention concerne également le traitement ou la prévention de l'ostéoporose, de l'atrophie cutanée, de l'atrophie épithéliale et de la muqueuse, ainsi que le traitement ou la prévention de symptômes urinaires ou vaginaux.

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