Method for enhancing the immunogenicity of an immunogenic...

Details Method for enhancing the immunogenicity of an immunogenic... Method for enhancing the immunogenicity of an immunogenic...

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 31/70 (2006.01) A61K 39/155 (2006.01) A61K 39/29 (2006.01) A61K 39/385 (2006.01) A61K 48/00 (2006.01) C07K 14/135 (2006.01) C12N 15/31 (2006.01) C12N 15/45 (2006.01) C12N 15/51 (2006.01)

Patent

CA 2204619

A method for enhancing the immunogenicity of an immunogen, antigen or hapten on delivery to a host, regardless of the delivery method, wherein said antigen or hapten is covalently coupled to a carrier molecule to form a complex, and the carrier molecule is a polypeptide fragment capable of specifically binding to mammalian serum albumin. The use of the resulting product as a drug is also disclosed.

La présente invention concerne un procédé pour améliorer l'immunogénicité d'un immunogène, d'un antigène ou d'un haptène, lorsqu'il est administré à un hôte, indépendamment du mode d'administration, caractérisé en ce que ledit antigène ou haptène est couplé de façon covalente à une molécule support, pour former un complexe, et en ce que cette molécule support est un fragment polypeptidique capable de se lier spécifiquement à la sérumalbumine de mammifère. Elle concerne également l'utilisation, à titre de médicament, du produit susceptible d'être ainsi obtenu.

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