Method for enriching fetal cells from maternal blood

Details Method for enriching fetal cells from maternal blood Method for enriching fetal cells from maternal blood

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01) C12N 5/06 (2006.01) C12Q 1/24 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) G01N 33/80 (2006.01)

Patent

CA 2081203

2081203 9116452 PCTABS00008 A method is provided for enriching fetal nucleated, erythroid cells from maternal blood comprising the steps of: (a) incubating a sample of maternal blood with an immobilized ligand capable of specifically binding to fetal nucleated, erythroid cells under conditions and for a time sufficient to allow specific binding of the ligand to the cells; (b) removing unbound blood products; and (c) incubating the bound cells in the presence of erythropoietin such that fetal cells are preferentially enriched.

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