Method for enrichment of selected rna molecules

C - Chemistry – Metallurgy – 12 – P

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C12P 19/34 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2750547

Improved methods of studying RNA molecules are provided. In particular, methods of treating mixtures of RNA molecules so as to enrich the mixture for a desired type of RNA molecule are provided. For example, the methods permit depletion of mRNA from complex mixtures to facilitate study of microRNAs in the mixture.

L'invention concerne des procédés améliorés d'étude de molécules d'ARN. En particulier, l'invention concerne des procédés consistant à traiter des mélanges de molécules d'ARN de façon à enrichir le mélange pour un type souhaité de molécule d'ARN. Par exemple, les procédés permettent l'appauvrissement d'ARNm de mélanges complexes pour faciliter l'étude de microARN dans le mélange.

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