Method for enzymatic production of glp-2(1-33) and...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/605 (2006.01) C07K 1/34 (2006.01) C12P 21/06 (2006.01)

Patent

CA 2485703

The invention provides methods for making peptides from a polypeptide containing at least one copy of the peptide using clostripain to excise the peptide from the polypeptide. The methods enable the use of a single, highly efficient enzymatic cleavage to produce any desired peptide sequence.

L'invention concerne des procédés de production de peptides à partir d'un polypeptide contenant au moins une copie du peptide à l'aide de clostripain pour exciser le peptide du polypeptide. Les procédés permettent l'utilisation d'un seul clivage enzymatique hautement efficace afin de produire n'importe quelle séquence peptidique voulue.

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