G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/70 (2006.01) A61B 5/05 (2006.01) G01N 33/493 (2006.01)
Patent
CA 2233626
Creatinine clearance is estimated in a patient by determining his or her body cell mass. In turn, the body cell mass of the patient is measured using bioimpedance analysis techniques. The patient's serum creatinine concentration is also measured. The body cell mass and the serum creatinine concentration provide an indication of actual creatinine clearance in the subject through use of a predictive formula. From this prediction, accurate dosages of potentially nephrotoxic medications can be appropriately prescribed.
On obtient des valeurs estimatives de la clairance de la créatinine chez un patient en déterminant sa masse cellulaire somatique, cette dernière étant, quant à elle, évaluée en faisant intervenir des techniques d'analyse d'impédance bioélectrique. On mesure également la teneur en créatinine du sérum du patient. La masse cellulaire somatique et la teneur en créatinine du sérum fournissent une indication de la clairance de la créatinine réelle chez le sujet par le biais d'une formule prédictive. A partir de cette prévision, il est possible de prescrire avec pertinence des posologies précises de médicaments potentiellement néphrotoxiques.
Kotler Donald P.
Sordillo Emilia M.
Blake Cassels & Graydon Llp
St. Luke's-Roosevelt Hospital
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