Method for estimating the growth potential of cerebral infarcts

Details Method for estimating the growth potential of cerebral infarcts Method for estimating the growth potential of cerebral infarcts

G - Physics

06

T

G06T 7/00 (2006.01)

Patent

CA 2656299

The invention relates to a method for automatic estimation of the growth potential of cerebral infarcts, particularly in the acute phase, that is to say in the six hours following survival of the stroke. The prior art includes several methods for predicting the growth of cerebral infarcts, but these methods are not yet standardized. The invention therefore proposes overcoming this problem by making available a method for estimating the growth potential of cerebral infarcts, which method comprises: a step (10) in which sequences of diffusion MRI images are obtained, a step (40) in which the apparent diffusion coefficient (ADC) is calculated at a multiplicity of points or voxels of the cortical parenchyma, and a step (30) which involves locating and delimiting the initial infarct and modelling the development of the infarct based on a growth model established by iterative minimization of a global energy index E defined by a linear combination of elementary energy parameters dependent on the intensity of the ADC.

L'invention concerne une méthode d'estimation automatique du potentiel de croissance des infarctus cérébraux en particulier en phase aiguë, c'est-à-dire dans les six heures suivant la survenue de l'accident ischémique cérébral. Il est connu de la technique quelques méthodes de prédiction de la croissance des infarctus cérébraux, mais ces méthodes ne sont pas encore standardisées. L'invention propose donc de remédier à ce problème en proposant une méthode d'estimation du potentiel de croissance des infarctus cérébraux gui comporte : une étape (10) acquisition de séquences d'images IRM de diffusion, une étape (40) calcul du coefficient de diffusion apparent (CDA) en une multitude de points ou voxels du parenchyme cortical, une étape (30) de localisation et délimitation de l'infarctus initial et modélisation de l'évolution de l'infarctus à partir d'un modèle de croissance établi par la minimisation itérative d'un indice d'énergie globale E défini par une combinaison linéaire de paramètres d'énergie élémentaires dépendant de l'intensité du CDA.

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