Method for evaluating microsatellite instability in a tumor...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2358366

A detection method for high throughput screening for tumor microsatellite instability. The method employs a panel of microsatellite loci and it is based on a fluorescent multiplex PCR system. The method provides a fast, sensitive, and cost-effective high throughput screening method of MSI detection. The method allows many samples to be processed in one day on a single polyacrylamide gel, and it utilizes much less nucleic acid sample than conventional methods.

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