Method for examining wt1-related disease

G - Physics – 01 – N

Patent

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G01N 33/53 (2006.01) G01N 33/574 (2006.01) C07K 16/30 (2006.01)

Patent

CA 2409208

The invention provides a method for testing a WT1-related disease, such as leukemia, a solid cancer, or an atypia, for diagnosing the disease, evaluating the course of cure and the prognosis of the disease more simply with high reliability, the method comprises measuring the amount of antibody against WT1 in a sample and using the measurement value and the time course of the value as a clinical marker for the testing.

L'invention concerne un procédé d'examen d'une maladie liée à WT1, qui permet de détecter une telle maladie, telle que la leucémie, un cancer solide ou une anomalie et de vérifier le processus de traitement et de pronostic plus facilement et avec une fiabilité accrue. Le procédé est caractérisé en ce que la quantité d'anticorps réagissant en contact de WT1 dans un échantillon est mesurée, et la valeur de la mesure et sa variation temporelle sont utilisées comme indices cliniques pour l'examen.

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