Method for expanding cd4+ cd25+ t regulatory cells

C - Chemistry – Metallurgy – 12 – N

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C12N 5/00 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2598631

A method for generating/expanding in vitro a CD4+CD25+ T regulatory (Tr) cell and the use thereof in the treatment of diseases associated with a cell- mediated immune response (including T- and antibody-mediated responses).

L'invention concerne un procédé destiné à générer/développer une cellule régulatoire (Tr) CD4+CD25+ in vitro et l'utilisation de ce procédé dans le traitement de maladies associées à une réponse immunitaire à médiation cellulaire (notamment des réponses à médiation anticorps et T).

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