Method for expression and isolation of biologically active...

Details Method for expression and isolation of biologically active... Method for expression and isolation of biologically active...

C - Chemistry, Metallurgy

12

N

C12N 15/85 (2006.01) A01K 67/027 (2006.01)

Patent

CA 2221453

A method for the directing expression of biologically active molecules in the urothelium via use of urothelial-specific promoters and a method for producing transgenic animals resulting in the expression of biologically active molecules that are secreted into their urine for subsequent recovery are provided.

Ce procédé permet l'expression de molécules biologiquement actives dans l'épithélium excréto-urinaire par l'utilisation de promoteurs spécifiques de cet épithélium, et un autre procédé permet d'obtenir des animaux transgéniques donnant lieu à l'expression de molécules biologiquement actives sécrétées dans leurs urines et récupérables ultérieurement.

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