Method for expression and secretion in bacillus

Details Method for expression and secretion in bacillus Method for expression and secretion in bacillus

C - Chemistry, Metallurgy

12

N

195/1.2, 195/1.2

C12N 15/00 (2006.01) C12N 1/20 (2006.01) C12P 21/02 (2006.01)

Patent

CA 1274480

Abstract A novel method for expressing and secreting a functional polypeptide in Bacillus, including the vectors and transformants for the practice thereof, is provided. The vectors comprise the transcriptional and translational activity sequence, and optionally the signal peptide coding sequence, of the Staphylococcus aureus nuclease gene. The vectors and transformants are useful for the production and secretion of human hormones such as human proinsulin.

491093

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