Method for extending the vascular dwell-time of particulate...

Details Method for extending the vascular dwell-time of particulate... Method for extending the vascular dwell-time of particulate...

A - Human Necessities

61

K

A61K 9/127 (2006.01) A61K 9/50 (2006.01) A61K 31/44 (2006.01) A61K 31/455 (2006.01) A61K 47/48 (2006.01) A61K 49/04 (2006.01) A61K 49/18 (2006.01)

Patent

CA 2123486

2123486 9309762 PCTABS00022 The present invention relates to a composition for increasing the vascular dwell-time of a particulate therapeutic or diagnostic agent in a mammal through the adjunct administration of an effective amount of the particulate therapeutic or diagnostic agent and an effective amount of a vascular dwell-time enhancing agent. Suitable therapeutic and diagnostic agents include those whose efficacy within the body is predicated on their ability to remain within or to be carried within the vascular compartment. Accordingly this method can be readily adapted for treating several diseases and disorders, including hypoxia, hypoxemia, anemia and cancer and for imaging selected regions of a mammal by various imaging techniques, including ultrasound imaging, X-ray imaging and MRI imaging.

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