Method for extracorporeal removal of a pathogenic microbe,...

A - Human Necessities – 61 – M

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A61M 1/34 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2630823

The present invention relates to a method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from mammalian blood/ use of a device comprising a carbohydrate immobilized on a solid substrate, said carbohydrate having a binding affinity for a pathogenic microbe, an inflammatory cell or an inflammatory protein, for extracorporeal removal of said pathogenic microbe, inflammatory cell or inflammatory protein from mammalian blood/ use of a carbohydrate having a binding affinity for a pathogenic microbe, an inflammatory cell or an inflammatory protein, wherein said carbohydrate is immobilized on a solid substrate, in the preparation of a device for treatment of a condition caused or aggravated by said pathogenic microbe, inflammatory cell or inflammatory protein/ and a method for treatment of a mammalian subject suffering from a condition caused or aggravated by a pathogenic microbe, an inflammatory cell or an inflammatory protein.

La présente invention concerne une méthode d~élimination extracorporelle d'un microbe pathogène, d~une cellule inflammatoire ou d~une protéine inflammatoire du sang d~un mammifère ; l~utilisation d'un appareil qui comprend un hydrate de carbone immobilisé sur un substrat solide, ledit hydrate de carbone possèdant une affinité de liaison pour un microbe pathogène, une cellule inflammatoire ou une protéine inflammatoire, pour élimination extracorporelle dudit microbe pathogène, de ladite cellule inflammatoire ou de ladite protéine inflammatoire du sang de mammifère ; l~utilisation d'un hydrate de carbone ayant une affinité de liaison pour un microbe pathogène, une cellule inflammatoire ou une protéine inflammatoire, ledit hydrate de carbone étant immobilisé sur un substrat solide, pour la préparation d'un appareil pour traiter une maladie causée ou aggravée par ledit microbe pathogène, ladite cellule inflammatoire ou ladite protéine inflammatoire ; et une méthode pour traiter un sujet mammifère souffrant d'une maladie causée ou aggravée par un microbe pathogène, une cellule inflammatoire ou une protéine inflammatoire.

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