C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07K 1/00 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2092432
2092432 9206217 PCTABS00011 Method for the sequencing of elements forming a linear or linearised and ordered biological sequence such as a DNA fragment, the method comprising the marking of a plurality of identical sequences by a set of specific markers, the efficiency of such marking being lower than 100 %, the sequential detection and identification of the markers associated with the elements of said sequences in order to obtain lacunar or incomplete sequences of marked elements, and the reconstitution of the complete sequence, by calculating from said lacunar sequences the probabilities of presence of elements in the complete sequence and by retaining the elements whose probabilities of presence approximate 1 or are equal to 1 whereas the probabilities of presence of other elements are close to 0 or equal to 0.
Ginot Frederic
Ruggiu Gilles
Bertin & Cie
Ginot Frederic
Marcus & Associates
Ruggiu Gilles
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