Method for formulating and immobilizing a protein matrix and...

C - Chemistry – Metallurgy – 12 – N

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C12N 11/00 (2006.01) A61B 5/00 (2006.01) C07K 1/107 (2006.01) C12N 11/02 (2006.01) C12Q 1/54 (2006.01) G01N 33/66 (2006.01)

Patent

CA 2457545

A method for formulating and immobilizing a protein and a protein matrix formed by the method. The protein matrix preparation method results in a physically and chemically stable protein matrix that has low swelling, non- leaching, high activity, and high mechanical strength properties. The method includes cross-linking and hardening the protein mixture and using a mold to form a protein into a desired shape and size.

L'invention concerne un procédé de formulation et d'immobilisation d'une protéine et une matrice protéique constituée au moyen dudit procédé. Le procédé de préparation de la matrice protéique permet d'obtenir une matrice protéique stable sur le plan physique et chimique, gonflant peu, exempte de lixivation et présentant une activité élevée et de bonnes propriétés de résistance mécanique. Le procédé consiste à réticuler et à faire durcir le mélange protéique et à utiliser un moule, aux fins de formation d'une protéine présentant une forme et des dimensions souhaitées.

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