A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A61K 9/14 (2006.01) A61K 9/28 (2006.01) B05D 1/04 (2006.01)
Patent
CA 2415082
A method is disclosed for formulating healthcare products, including solid pharmaceutical compositions, while avoiding instability caused ba interaction of the active ingredient with excipients. The method comprises the steps of: (a) selecting an active ingredient that loses stability or potency upon interaction with pharmaceutical excipients; and (b) depositing the active ingredient, preferably electrostatically, as a dry powder substantially free of excipients, onto a pharmaceutically acceptable polymer substrate.
L'invention concerne un procédé de formulation de produits d'hygiène personnelle, notamment des compositions pharmaceutiques solides, qui permet d'éviter toute instabilité provoquée par l'interaction de l'ingrédient actif avec les excipients. Ledit procédé consiste : (a) à choisir un ingrédient actif qui perd de sa stabilité ou de son activité en cas d'interaction avec des excipients pharmaceutiques ; et (b) à déposer l'ingrédient actif, de préférence électrostatiquement, sous la forme d'une poudre sèche sensiblement exempte d'excipients, sur un substrat polymère pharmaceutiquement acceptable.
Chrai Suggy S.
Harmon Troy M.
Katdare Ashok
Murari Ramaswamy
Delsys Pharmaceutical Corporation
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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