Method for generating an animal homozygous for a genetic...

A - Human Necessities – 01 – K

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A01K 67/027 (2006.01) C12N 5/073 (2010.01) C12N 15/873 (2010.01) C12N 15/00 (2006.01) C12N 15/87 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2583750

Methods of generating modified embryos and mammals by introduction of donor cells into an early stage embryo are provided, such that the resulting embryo and animal generated therefrom has a significant or complete contribution to all tissues from the donor cells and is capable of transmitting the donor cell DNA.

Méthodes de production d'embryons et de mammifères modifiés par introduction de cellules d'un donneur dans un embryon au stade précoce, de manière que l'embryon obtenu et l'animal en résultant présentent une contribution considérable ou complète des cellules du donneur à tous les tissus et soit capable de transmettre l'ADN cellulaire du donneur.

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