Method for identification of a ligand whereby receptor...

Details Method for identification of a ligand whereby receptor... Method for identification of a ligand whereby receptor...

G - Physics

01

N

G01N 33/566 (2006.01) G01N 33/557 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2485825

The present invention relates to the use of an assay that measures receptor residence time of a ligand on its receptor in vitro for the identification of a ligand for that receptor predicted to be efficacious in vivo in the treatment of a disease that responds to modulation of that receptor's natural function.

L'invention concerne l'utilisation d'un dosage biologique qui mesure le temps de séjour récepteur d'un ligand sur son récepteur <i>in vitro</i> pour identifier un ligand pour le récepteur prédit comme efficace <i>in vivo</i> dans le traitement d'une maladie répondant à la modulation de cette fonction naturelle du récepteur.

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