G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/573 (2006.01) A61P 3/10 (2006.01) C12N 9/12 (2006.01) C12Q 1/42 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2446284
The invention relates to the use of the human "MAP kinase interacting kinases" Mnk2a or Mnk2b in methods for identification of pharmaceutically useful agents, in particular agents useful for the treatment of type II diabetes. The invention also relates to methods of treating or preventing medical conditions relating to insulin resistance by modulating the expression or activity of Mnk2a or Mnk2b.
La présente invention concerne l'utilisation des "kinases à interaction avec les kinases MAP" Mnk2a ou Mnk2b humaines dans des méthodes permettant l'identification d'agents pharmaceutiquement acceptables, en particulier d'agents utiles pour le traitement des diabètes de type II. Cette invention concerne également des méthodes permettant de traiter ou de prévenir des états pathologiques associés à la résistance à l'insuline par modulation de l'expression ou de l'activité de Mnk2a ou de Mnk2b.
Bendz Christina
Lake Staffan
Biovitrum Ab
Biovitrum Ab (publ)
Fetherstonhaugh & Co.
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