Method for identifying compounds affecting rna/rna binding...

C - Chemistry – Metallurgy – 12 – Q

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2262920

It has been discovered that a single set of conditions can be used to detect nearly every interaction of RNA binding proteins and RNA molecules. Prior to this discovery it was thought that each specific interaction required separate optimized conditions in order to be detected. Assays employing the disclosed universal conditions are useful for identifying RNA binding proteins that interact with specific RNA molecules of interest, detecting RNA molecules that interact with specific RNA binding proteins of interest, identifying RNA binding proteins active in certain cell types and under certain physiological conditions, identifying specific regions of an RNA molecule that interact with RNA binding proteins. Screening assays employing the disclosed universal conditions are useful for identifying compounds that modulate RNA/RBP interactions of interest.

On a découvert qu'un seul ensemble de conditions est utilisable afin de détecter pratiquement chaque interaction de protéine de fixation d'ARN et de molécules d'ADN. Préalablement à cette découverte, on pensait que chaque interaction spécifique nécessitait des conditions optimisées, de manière à être détectée. Des méthodes de mise en application de ces conditions universelles sont utiles afin d'identifier les protéines de fixation d'ARN exerçant une interaction avec des molécules spécifiques d'ARN, de détecter des molécules d'ARN exerçant une interaction avec des protéines spécifiques de fixation d'ARN, d'identifier des protéines de fixation d'ARN actives dans certains types de cellules et dans certaines conditions physiologiques, d'identifier des zones spécifiques d'une molécule d'ARN exerçant une interaction avec des protéines de fixation d'ARN. Des méthodes de criblage mettant en application ces conditions universelles sont utiles afin d'identifier des composés modulant des interactions entre ARN et RPB.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Method for identifying compounds affecting rna/rna binding... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for identifying compounds affecting rna/rna binding..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for identifying compounds affecting rna/rna binding... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1867139

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.