Method for identifying herbicidally active substances

Details Method for identifying herbicidally active substances Method for identifying herbicidally active substances

C - Chemistry, Metallurgy

12

N

C12N 15/29 (2006.01) A01H 5/00 (2006.01) A01K 67/027 (2006.01) A01N 61/00 (2006.01) C07K 14/415 (2006.01) C12N 15/82 (2006.01) C12Q 1/00 (2006.01) C12Q 1/18 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2437937

The invention relates to genes and methods for isolating genes coding for gene products, the lack of said gene products leading to significantly delayed growth and/or completely stunted growth at the embryonic stage of Arabidopsis thaliana. The invention relates to the use of said genes and the gene products coded thereby for discovering novel herbicides. The invention also relates to the use of the genes and gene products identified here for producing plants which are resistant to herbicides. The invention further relates to a method for identifying herbicidally active substances, substances identified according to said method and the use of said substances as herbicides. Furthermore, the invention relates to nucleic acid constructs, vectors, organisms containing said nucleic acid constructs and/or vectors, and especially transgenic plants containing said nucleic acid constructs and/or vectors. Disclosed is also a method for identifying antagonists and the use thereof, antibodies and antisense RNA molecules, and agents containing a herbicide substance which is isolated according to the inventive methods. Finally, the invention relates to compositions containing the antibodies, the antisense nucleic acids and/or the antagonists.

L'invention concerne des gènes et des procédés pour isoler des gènes codant pour des produits géniques dont l'absence entraîne une croissance considérablement retardée ou un arrêt complet de la croissance au niveau embryonnaire de Arabidopsis thaliana. L'invention concerne l'utilisation de ces gènes et des produits géniques ainsi codés pour la découverte de nouveaux herbicides. L'invention concerne également l'utilisation des gènes et produits géniques identifiés ici pour la production de plantes résistant à des herbicides. L'invention concerne en outre un procédé pour l'identification de substances à action herbicide, des substances identifiées selon ce procédé, ainsi que leur utilisation comme herbicide. L'invention concerne aussi des structures d'acides nucléiques, des vecteurs, des organismes contenant ces structures d'acides nucléiques ou ces vecteurs, et spécifiquement des plantes transgéniques contenant ces structures d'acides nucléiques ou ces vecteurs. L'invention concerne également un procédé pour l'identification d'antagonistes et leur utilisation, des anticorps et des molécules d'ARN antisens, ainsi que des produits contenant une substance herbicide isolée selon les procédés de l'invention. L'invention concerne enfin des compositions contenant l'anticorps, l'acide nucléique antisens ou l'antagoniste.

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