G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/53 (2006.01) A61K 49/00 (2006.01) C12P 19/34 (2006.01) C12P 21/06 (2006.01)
Patent
CA 2611969
Methods for identifying modulators of KEAH6 are described. The methods are particularly useful for identifying analytes that antagonize KEAH6's effect on processing of amyloid precursor protein to A.beta. peptide and thus useful for identifying analytes that can be used for treating Alzheimer disease.
L'invention concerne des méthodes destinées à identifier des modulateurs de KEAH6. Ces méthodes sont particulièrement utiles pour identifier des analytes antagonisant l'effet de KEAH6 sur la maturation de la protéine précurseur amyloïde en peptide A.beta., et, par conséquent, sont utiles pour identifier des analytes pouvant être utilisés pour traiter la maladie d'Alzheimer.
Majercak John M.
Ray William J.
Stone David J.
Merck & Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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