G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/53 (2006.01) A01N 37/18 (2006.01) A61K 39/395 (2006.01) C12Q 1/34 (2006.01) C12Q 1/37 (2006.01) G01N 33/566 (2006.01) G01N 33/567 (2006.01)
Patent
CA 2607234
Methods for identifying modulators of NOAH10 are described. The methods are particularly useful for identifying analytes that antagonize NOAH10~s effect on processing of amyloid precursor protein (APP) to amyloid beta (A.beta.) peptide and are useful for identifying analytes that can be used for treating Alzheimer disease.
La présente invention concerne des procédés d~identification de modulateurs de NOAH10. Ces procédés sont particulièrement utiles pour l~identification des analytes qui agissent en tant qu~antagonistes sur les effets de NOAH10 lors du traitement de la protéine du précurseur de l~amyloïde (APP) en peptide bêta amyloïde (A.beta.) et sont utiles pour l~identification des analytes qui peuvent être utilisés pour le traitement de la maladie d~Alzheimer.
Majercak John M.
Ray William J.
Stone David J.
Merck & Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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