Method for identifying pde10 modulators

Details Method for identifying pde10 modulators Method for identifying pde10 modulators

C - Chemistry, Metallurgy

12

N

C12N 9/88 (2006.01) C12N 5/10 (2006.01) C12N 15/60 (2006.01) C12N 15/62 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2604349

The invention relates to a novel polypeptide, containing the GAF A domain and GAF B domain of a human phospho-diesterase 10 (PDE10) and the catalytic domain of an adenylate cyclase and to the use of said polypeptide in a method for identifying PDE10 modulators.

L'invention concerne un nouveau polypeptide, contenant un domaine GAF<SUB>A</SUB> d'une phosphodiéstérase humaine 10 (PDE10) et le domaine catalytique d'une adénylatcyclase, ainsi que l'utilisation dudit polypeptide dans un procédé permettant d'identifier des modulateurs de la PDE10.

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