G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/543 (2006.01) G01N 33/92 (2006.01)
Patent
CA 2423822
The invention relates to a method for immobilising lipid layers on the surfaces of solid bodies, according to which the surfaces of said solid bodies are modified in such a way that the characteristics of the lipid layers deposited thereon, in particular with regard to their diffusive capacity, largely resemble those of non-immobilised lipid layers. According to the method, the surface of the solid body is first modified by means of molecules, in such a way that a substantially hydrophilic surface is formed. In a second step, lipid layers, in particular, lipid bilayers are deposited on said modified surface.
L'invention concerne un procédé pour l'immobilisation de couches lipidiques sur des surfaces de solides, selon lequel les surfaces des solides sont modifiées de façon que les caractéristiques des couches lipidiques déposées dessus correspondent largement, notamment en ce qui concerne leur diffusibilité, aux caractéristiques de couches lipidiques non immobilisées. A cet effet, la surface du solide est d'abord modifiée à l'aide de molécules de façon qu'une surface pratiquement hydrophile se forme. Lors d'une deuxième étape du procédé, des couches lipidiques, notamment des doubles couches lipidiques, sont déposées sur cette surface modifiée.
Noller Joachim
Schmitt Johannes
Nimbus Biotechnologie Gmbh
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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