Method for immunotherapy of tumors

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/0784 (2010.01) A01K 67/027 (2006.01) A61K 35/14 (2006.01) A61K 39/00 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2534377

A method for making dendritic cells reactive to an antigen comprises obtaining a sample of dendritic cells and contacting the cells with the antigen and at least one Toll-like receptor stimulant. Dendritic cells activated by this method provide a means for treating tumors and for creating animal models of autoimmune diseases.

Un procédé permettant de rendre des cellules dendritiques réactives par rapport à un antigène consiste à obtenir un échantillon de cellules dendritiques et à les mettre en contact avec l'antigène et au moins un stimulateur du récepteur de type Toll. Les cellules dendritiques activées selon ce procédé permettent de traiter des tumeurs et de créer des modèles animaux de maladies auto-immunes.

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