Method for improving human monoclonal antibody production

C - Chemistry – Metallurgy – 12 – P

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C12P 21/08 (2006.01) C07K 16/00 (2006.01) C07K 16/12 (2006.01) C12N 5/10 (2006.01) C12N 5/18 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2066720

2066720 9104336 PCTABS00003 Human monoclonal antibodies are expressed by recombinant mammalian cells transformed with vectors containing genes encoding the heavy and light chains of the human monoclonal antibodies. The genes were isolated from a genomic library constructed from a human/human or human/murine hybridoma which produces the antibodies.

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