G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/52 (2006.01) C12Q 1/25 (2006.01) G01N 33/558 (2006.01) G01N 33/66 (2006.01) G01N 33/68 (2006.01) G01N 33/70 (2006.01)
Patent
CA 2250622
Disclosed is an improved method for determining the concentration of a first analyte in a fluid test sample as a function of a second analyte also present in the sample whose concentration in the fluid sample is clinically related to that of the first analyte. The method involves determining the concentration of the first analyte, and, if this concentration is outside of its useful analytical range, dividing this concentration by the normal concentration of the second analyte. This method of ratioing the concentrations of the first and second analyte is advantageous because accuracy is increased with fewer false positive and false negative results being reported.
Divulgation d'une méthode améliorée pour déterminer la concentration d'un premier analyte dans un échantillon d'essai de fluide comme fonction d'un second analyte également présent dans l'échantillon et dont la concentration dans l'échantillon de fluide est cliniquement reliée à celle du premier analyte. La méthode consiste à déterminer la concentration du premier analyte et, si cette concentration se trouve à l'extérieur de sa plage analytique utile, à la diviser par la concentration normale du second analyte. Cette méthode utilisant le rapport des concentrations du premier et du second analytes est avantageuse en raison de sa plus grande exactitude et du nombre réduit de faux positifs et de faux négatifs.
Messenger Koleen K.
Pugia Michael J.
Wallace Jane F.
Corporation Bayer
Osler Hoskin & Harcourt Llp
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