Method for improving the dissolution profile of a...

A - Human Necessities – 61 – K

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A61K 9/14 (2006.01) A01N 25/14 (2006.01) A61J 3/02 (2006.01) B01J 2/00 (2006.01)

Patent

CA 2759104

The present invention relates to a method for improving the dissolution profile of a biologically active material comprising the steps of dry milling a solid biologically active material and a millable grinding matrix in a mill comprising a plurality of milling bodies, for a time period sufficient to produce particles of the biologically active material dispersed in an at least partially milled grinding material.

La présente invention concerne un procédé d'amélioration du profil de dissolution d'une matière biologiquement active qui comprend les étapes de broyage à sec d'une matière solide biologiquement active et d'une matrice de broyage pouvant être broyée dans un broyeur comprenant des corps de broyage, pendant une durée suffisante pour produire des particules de la matière biologiquement active dispersées dans une matière de broyage au moins partiellement broyée.

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