G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/569 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2713411
Method for in vitro detection and/or quantification and/or identification of infectious compounds present in a fluid medium M constituting a biological material, in which method a suspension of microbeads of solid polymer material capable of binding proteins is prepared; the microbeads are loaded with ß2GPI proteins by coupling with a sufficient amount of ß2GPI proteins; said microbeads are brought into contact with the fluid medium M while adding ions of at least one oxidizing metal, so as to bind the infectious compounds to the ß2GPI proteins; the microbeads thus prepared are separated from their suspension medium, so as to obtain a residue; and the infectious compounds of the residue are detected and/or quantified and/or identified.
Procédé de détection et/ou de quantification et/ou d'identification in vitro de composés infectieux présents dans un milieu fluide M constituant un matériau biologique, procédé dans lequel on prépare une suspension de microbilles de matériau polymère solide susceptible de fixer des protéines; on assure le chargement des microbilles avec des protéines .beta.2GPI par couplage avec une quantité suffisante de protéines .beta.2GPI; on met en contact lesdites microbilles avec le milieu fluide M en ajoutant des ions d'au moins un métal oxydant, pour assurer une fixation des composés infectieux sur les protéines .beta.2GPI; on sépare les microbilles ainsi préparées de leur milieu de suspension, pour obtenir un résidu; et on détecte et/ou quantifie et/ou identifie les composés infectieux du résidu.
Apoh Technologies Sa
Robic
LandOfFree
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