Method for in vitro production of three-dimensional vital...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 5/077 (2010.01) A61K 35/32 (2006.01) A61P 19/00 (2006.01) C12N 5/02 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2403120

The invention relates to an extremely simply method for in vitro production of three-dimensional, vital and mechanically stable cartilage or bone tissue and to the use thereof as transplant material in the treatment of cartilage or bone defects and degenerative diseases such as rheumatism or arthrosis, in addition to the use thereof in testing active substances and physical factors. The object of the invention is also cartilage or bone tissue thus produced and therapeutic preparations e.g. injection solutions containing said tissue.

La présente invention concerne un procédé extrêmement simple permettant de produire in vitro du tissu cartilagineux ou osseux tridimensionnel vivant et mécaniquement stable, et son utilisation comme matière de greffe dans le cadre du traitement des défaillances cartilagineuses ou osseuses et de maladies dégénératives telles que le rhumatisme ou l'arthrose, ainsi que son utilisation pour tester des substances actives et des facteurs physiques. L'invention a également pour objet le tissu cartilagineux ou osseux ainsi obtenu et des préparations thérapeutiques, telles que des solutions d'injection, qui contiennent ce tissu.

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