Method for inactivating pathogens, especially viruses, in a...

Details Method for inactivating pathogens, especially viruses, in a... Method for inactivating pathogens, especially viruses, in a...

A - Human Necessities

61

K

A61K 38/48 (2006.01) A61L 2/00 (2006.01) C12N 9/74 (2006.01)

Patent

CA 2285976

The invention relates to a method for inactivating pathogens, especially viruses, in a biological material, by means of incubation with a chemical agent. The invention is characterized in that the incubation takes place in the presence of an eluotropic salt corresponding to an NaCl concentration of at least 200 mmole/l, preferably at least 300 mmole/l. The invention also relates to a preparation containing a prothrombin complex and purified by chromatography.

L'invention concerne un procédé de neutralisation d'agents pathogènes, notamment de virus, dans un matériau biologique, par incubation avec un agent chimique. Ce procédé est caractérisé en ce que l'incubation est réalisée en présence d'un sel éluotrope correspondant à une concentration de NaCL d'au moins 200 mmol/l, de préférence, 300 mmol/l. L'invention concerne également une préparation contenant un complexe de prothrombine, purifiée par chromatographie.

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