Method for increasing expression and reducing expression...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/87 (2006.01) A01H 4/00 (2006.01) A01H 5/00 (2006.01) A01H 7/00 (2006.01) C07K 14/395 (2006.01) C12N 5/10 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2147006

Disclosed is a method of making recombinant plant cells having reduced variability of expression and increased levels of expression of foreign genes therein. The method comprises (a) providing a plant cell capable of regeneration; (b) transforming the plant cell with a DNA construct comprising an expression cassette, which construct comprises, in the 5' to 3' direction, a transcription initiation region, a structural gene positioned downstream from the transcription initiation region and operatively associated therewith, and a scaffold attachment region positioned either 5' to the transcription initiation region or 3' to the structural gene, the expression cassette subject to the proviso that T-DNA borders are excluded therefrom. DNA constructs and vectors employed in carrying out the foregoing method are also disclosed, along with plant cells and plants produced thereby.

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