C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 21/00 (2006.01) C12N 1/38 (2006.01) C12N 5/00 (2006.01) C12N 9/72 (2006.01) C12N 15/67 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2324385
The production of a physiologically active substance by a normal, transfected or transformed cultured cell can be increased by culturing the cell in a culture medium containing cobalt and molybdenum. The culture medium is one ordinarily selected for growing those types of cells which produce a desired, physiologically active substance, e.g., a recombinant growth factor of a monoclonal antibody. When cobalt and molybdenum are included in any of these growth media, a substantial improvement in the production of a physiologically active substance by the cells can be observed. Compositions and methods utilizing cobalt and molybdenum as additives for culture media are described.
Riches Mckenzie & Herbert Llp
Welfide Corporation
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