Method for inducing cell death with carbonyl scavengers

Details Method for inducing cell death with carbonyl scavengers Method for inducing cell death with carbonyl scavengers

A - Human Necessities

61

K

A61K 31/195 (2006.01) A61K 31/155 (2006.01)

Patent

CA 2557666

Carbonyl scavengers, which have been recognized for their ability to react with reactive carbonyl species, have been implicated as agents that can accelerate or induce the death of abnormal cells without having a parallel effect on normal cells. As such, they are useful therapeutic agents in cases where the acceleration or induction of cell death is desirable, such as in cells where the normal apoptotic pathways have been disrupted and where hyperproliferative cell growth occurs.

Les piégeurs de carbonyle, qui ont été reconnus pour leur capacité à réagir avec des espèces carbonyle réactives, ont été impliqués en tant qu'agents pouvant accélérer ou induire la mort de cellules anormales sans qu'ils aient un effet parallèle sur les cellules normales. En tant que tels, ils constituent des agents thérapeutiques efficaces lorsque l'accélération ou l'induction de la mort cellulaire est souhaitable, comme dans des cellules où les voies apoptotiques normales ont été interrompues et où une croissance de cellules hyperproliférantes apparaît.

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