Method for inducing mucosal humoral and cell-mediated immune...

Details Method for inducing mucosal humoral and cell-mediated immune... Method for inducing mucosal humoral and cell-mediated immune...

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 39/02 (2006.01) A61K 39/12 (2006.01) A61K 39/39 (2006.01) A61P 31/00 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2601358

Described are methods for inducing both a mucosal and a systemic immune response in the respiratory, digestive or urogenital tracts of a mammal to a microbial pathogen. The methods comprise topically administering onto the sublingual mucosa of the mammal an amount of an antigen effective to induce the mucosal and systemic immune responses and a pharmaceutically acceptable carrier or diluent. Pharmaceutical formulations and dosage forms for immunizing a mammal against a microbial pathogen to elicit a mucosal and systemic immune response in the respiratory, digestive or urogenital tracts are also described.

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