Method for inhibiting aromatase

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/415 (2006.01) A61K 31/41 (2006.01)

Patent

CA 2091709

ABSTRACT OF THE DISCLOSURE This invention provides a method of inhibiting aromatase and treating of estrogen-dependent diseases in a patient by administering azole derivatives as nonsteroidal inhibitors. The azole derivative has the formula Image where R1 is a hydrogen or a (C1-C5) alkyl; R2 is a hydrogen or a (C1-C5) alkyl; R3 is any of a halogen, a (C1-C5) alkyl, a haloalkyl, a phenyl, a cyano, or nitro; n is 0 to 5; and Y is a nitrogen atom or CH.

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