A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01)
Patent
CA 2371421
The invention relates to a method for inhibiting cell functioning for use in anti-inflammatory and anti-tumour therapies in the body of a warm-blooded living being, which comprises administering to said being a drug comprising, in a quantity effective for said therapies, a substance that specifically recognizes the extracellular domain of SIRP (anti-SIRP substance) and that inhibits the functioning of pathologic myeloid cells. The invention further relates to a drug to be used in the above method and to the active substance of said drug.
L'invention concerne une méthode d'inhibition du fonctionnement des cellules, s'utilisant dans des thérapies anti-inflammatoires et anti-tumorales appliquées au corps d'un patient. Ladite méthode consiste à administrer au patient un médicament comprenant, en quantité efficace pour lesdites thérapies, une substance qui reconnaît plus particulièrement le domaine extracellulaire SIRP (protéine régulatrice de signal) (substance anti-SIRP), et qui inhibe le fonctionnement des cellules myéloïdes pathologiques. L'invention concerne également un médicament utilisé dans ladite méthode, et la substance active de ce médicament.
Dijkstra Christine Diederike
Van Den Berg Timo Kars
Faculteit Der Geneeskunde Van de Vrije Universiteit
Fetherstonhaugh & Co.
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