Method for inhibiting nucleoside and nucleobase transport...

A - Human Necessities – 61 – K

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A61K 31/495 (2006.01) A61K 31/496 (2006.01)

Patent

CA 2172830

A method for inhibiting nucleoside and nucleobase transport in mammalian cells, as well as to a method for inhibition of virus replication and augmenting phosphorylation of nucleoside analogues, are disclosed, wherein each method uses, as the active agent, a carbostyril derivative.

L'invention se rapporte à un procédé d'inhibition du transport des nucléosides et nucléobases dans des cellules mammaliennes, ainsi qu'à un procédé d'inhibition de la réplication de virus et d'intensification de la phosphorylation d'analogues de nucléosides, chaque procédé mettant en oeuvre, comme agent actif, un dérivé de carbostyrile.

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