Method for inhibiting the growth of antibiotic-resistant of...

A - Human Necessities – 61 – K

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Details

A61K 31/045 (2006.01) A01N 31/02 (2006.01) A61K 9/06 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2529287

A method for inhibiting the growth of multiple-resistant bacteria comprises the topical administration of a pharmaceutical composition comprising 15% by weight or more of pentane-1,5-diol and a pharmaceutical acceptable carrier. Also disclosed is a method of preparing a corresponding medicament. A method of disinfecting a surface contaminated with multiple-resistant bacteria comprises providing a disinfecting composition comprising 15% or more by weight of pentane-1,5-diol and an aqueous carrier, applying the composition to the surface; optionally, keeping it in contact with the surface for a period of time from 5 min to 24 hrs at ambient temperature, and rinsing the surface with water or an aqueous detergent composition. Also disclosed is the use of a corresponding bacteriostatic composition.

L'invention concerne une méthode destinée à inhiber la croissance de bactéries multirésistantes. Cette méthode consiste à administrer topiquement une composition pharmaceutique contenant au moins 15 % en poids de pentane-1,5-diol et un excipient pharmaceutiquement acceptable. L'invention concerne également un procédé de préparation d'un médicament correspondant. L'invention concerne encore une méthode de désinfection d'une surface contaminée par des bactéries multirésistantes. Ledit procédé consiste : à obtenir une composition désinfectante contenant au moins 15 % en poids de pentane-1,5-diol et un excipient aqueux ; à appliquer cette composition sur ladite surface ; facultativement à la maintenir en contact avec cette surface pendant une durée comprise entre 5 minutes et 24 heures, à température ambiante ; et à rincer la surface contaminée avec de l'eau ou avec une composition détergente aqueuse. L'invention concerne encore l'utilisation d'une composition bactériostatique correspondante.

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