A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/46
A61K 49/00 (2006.01) A61K 49/18 (2006.01) G01R 33/28 (2006.01) G01R 33/465 (2006.01)
Patent
CA 1336165
A diagnostic imaging agent is provided for use in conjunction with a magnetic resonance imaging system for the imaging of spacial oxygen distribution in tissue. The imaging agent is comprised of a complex of oxygen-17, a biologically acceptable liquid carrier, such as a perfluori- nated compound, and an emulsifying agent, and wherein the agent has an average particle size of less than about 0.6 microns and an ionic composition essentially equal to that of blood. Useful information can be obtained, and in certain instances, therapy administered by a non-evasive imaging technique relative to tissue perfusion by 19F-NMR (imaging of 19F) and oxygen utilization by 1H-NMR (imaging of H217O as a metabolite).
608686
Arai Toshiyuki
Gupte Pradeep
Lasker Sigmund E.
Arai Toshiyuki
Gupte Pradeep
Lasker Sigmund E.
Smart & Biggar
LandOfFree
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