Method for isolating cell free apoptotic or fetal nucleic acids

Details Method for isolating cell free apoptotic or fetal nucleic acids Method for isolating cell free apoptotic or fetal nucleic acids

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/00 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2714212

The present invention provides methods for isolating cell free nucleic acid, e.g., apoptotic or fetal nucleic acids and methods of detecting neoplastic cells or identifying the genetic composition of a fetus. The invention also provides magnetic particles comprising an anti-DNA antibody, and kits comprising the magnetic particles.

La présente invention concerne des procédés d'isolement d'acides nucléiques sans cellules, par exemple d'acides nucléiques apoptotiques ou ftaux, ainsi que des procédés de détection de cellules néoplasiques ou d'identification de la composition génétique d'un ftus. L'invention concerne également des particules magnétiques comprenant un anticorps anti-ADN et des nécessaires comprenant lesdites particules magnétiques.

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