Method for labeling antibodies with a metal ion

Details Method for labeling antibodies with a metal ion Method for labeling antibodies with a metal ion

A - Human Necessities

61

K

167/101, 167/40

A61K 51/10 (2006.01)

Patent

CA 1317544

METHOD FOR LABELING ANTIBODIES WITH METAL ION Abstract of the Disclosure A method for labeling a sulfhydryl con- taining antibody or antibody fragment with tech- netium-99m is disclosed. The method comprises contacting an antibody mixture comprised of a sulfhydryl containing antibody or antibody fragment and a reducing agent with technetium-99m is an oxidized state. The anibody mixture further con- tains a water soluble ligand. A one vial method and kit for labeling a sulfhydryl containing antibody or antibody fragment with technetium-99m is also disclosed.

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