Method for loading a beneficial agent into a medical device

Details Method for loading a beneficial agent into a medical device Method for loading a beneficial agent into a medical device

A - Human Necessities

61

F

A61F 2/06 (2006.01)

Patent

CA 2603332

A system for delivery of a beneficial agent in the form of a viscous liquid or paste allows holes in a medical device to be loaded in a single step process. Another system for loading a beneficial agent into holes in a medical device includes a punch system for punching plugs of beneficial agent from a thin sheet into the holes in the medical device. The loading of a beneficial agent in a paste form or from a thin film also provides the ability to deliver large and potentially sensitive molecules including proteins, enzymes, antibodies, antisense, ribozymes, gene/vector constructs, and cells including endothelial cells.

L'invention concerne un système servant à administrer un agent à effet bénéfique, sous forme d'un liquide ou d'une pâte visqueuse, système comportant des trous dans un dispositif médical servant au chargement en une seule étape. Un autre système de chargement d'un agent à effet bénéfique dans des trous dans un dispositif médical comprend un système de matriçage pour l'enfoncement de pastilles d'agent à effet bénéfique, à partir d'une feuille mince, dans les trous du dispositif médical. Le chargement d'un agent à effet bénéfique sous forme de pâte ou à partir d'un film mince confère au système l'aptitude à administrer de grandes molécules, potentiellement sensibles, comprenant des protéines, des enzymes, des anticorps, des antisens, des ribozymes, des structures de gènes/vecteurs, et des cellules renfermant des cellules endothéliales.

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